Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that protects older people against aspects of aging and a range of diseases. Their findings, which are published in eBioMedicine, demonstrate ...
Mar 15, 2022
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Making a drug is like trying to pick a lock at the molecular level. There are two ways in which you can proceed. You can try thousands of different keys at random, hopefully finding one that fits. The pharmaceutical industry ...
Apr 26, 2018
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Pancreatic cancer carries a very bleak prognosis for patients. However, a recent breakthrough by two research teams, including one at the Hôpital Maisonneuve-Rosemont (CIUSSS-EST, Montreal) and University of Montreal, has ...
Feb 25, 2016
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Regular infusions of a peptide that can selectively seek out and destroy broken-down cells that hamper proper tissue renewal, called senescent cells, showed evidence of improving healthspan in naturally-aged mice and mice ...
Mar 23, 2017
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Unraveling the links among obesity, aging, telomere lengths and metabolic diseases is the subject of the study published today in Nature Metabolism by a collaborative research team at The University of Texas Health Science ...
Dec 15, 2020
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A team of researchers affiliated with a large number of institutions in Japan has developed a vaccine that tricks the immune system into removing senescent cells. In their paper published in the journal Nature Aging, the ...
A protein has been found to have a previously unknown role in the ageing of cells, according to an early study by Queen Mary University of London (QMUL). The researchers hope that the findings could one day lead to new treatments ...
Mar 7, 2017
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Chronic inflammation, closely associated with frailty and age-related diseases, is a hallmark of aging. Mayo Clinic researchers have discovered that inhibiting key enzyme pathways reduces inflammation in human cells in culture ...
Nov 2, 2015
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Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age.
Sep 13, 2018
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Mayo Clinic researchers have reported a causal link between senescent cells - the cells associated with aging and age-related disease - and bone loss in mice. Targeting these cells led to an increase in bone mass and strength. ...
Aug 21, 2017
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