Diseases, Conditions, Syndromes

Early sepsis detection with infrared

Sepsis is a major risk factor for patient death among those in intensive care not suffering from heart problems. In fact, it is the eleventh cause of death overall in the U.S.. It arises when infection causes a breakdown ...

Diseases, Conditions, Syndromes

What is sepsis and how can it be treated?

Sepsis, colloquially known as blood poisoning, occurs as a result of an infection, usually from bacteria. Bacteria can enter the blood stream via an open wound, from another part of the body after a surgical procedure, or ...

Diseases, Conditions, Syndromes

Improving outcomes for sepsis patients

More than 1 million sepsis survivors are discharged annually from acute care hospitals in the United States. Although the majority of these patients receive post-acute care (PAC) services, with over a third coming to home ...

Genetics

Genes linked to death from sepsis identified in mice

Sepsis is a life-threatening condition that occurs when the body's immune response to infection spirals out of control. Bacteria in the bloodstream trigger immune cells to release powerful molecules called cytokines to quickly ...

Diseases, Conditions, Syndromes

First ever state sepsis regulation in US tied to lower death rates

Death rates from sepsis fell faster in New York than expected—and faster than in peer states—following the introduction of the nation's first state-mandated sepsis regulation, according to an analysis led by University ...

Medications

Using a common anticonvulsant to counteract inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis. A chromosomal protein called high-mobility group box 1 (HMGB1), secreted by immune and dying ...

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Sepsis

Sepsis is a serious medical condition characterized by a whole-body inflammatory state (called a systemic inflammatory response syndrome or SIRS) and the presence of a known or suspected infection. The body may develop this inflammatory response to microbes in the blood, urine, lungs, skin, or other tissues. An incorrect layman's term for sepsis is blood poisoning, more aptly applied to Septicemia, below.

Septicemia (also septicæmia [sep⋅ti⋅cæ⋅mi⋅a], or erroneously Septasemia and Septisema) is a related but deprecated (formerly sanctioned medical) term referring to the presence of pathogenic organisms in the blood-stream, leading to sepsis. The term has not been sharply defined. It has been inconsistently used in the past by medical professionals, for example as a synonym of bacteremia, causing some confusion. The present medical consensus is therefore that the term[which?] is problematic and should be avoided.

Sepsis is usually treated in the intensive care unit with intravenous fluids and antibiotics. If fluid replacement is insufficient to maintain blood pressure, specific vasopressor drugs can be used. Artificial ventilation and dialysis may be needed to support the function of the lungs and kidneys, respectively. To guide therapy, a central venous catheter and an arterial catheter may be placed. Sepsis patients require preventive measures for deep vein thrombosis, stress ulcers and pressure ulcers, unless other conditions prevent this. Some patients might benefit from tight control of blood sugar levels with insulin (targeting stress hyperglycemia), low-dose corticosteroids or activated drotrecogin alfa (recombinant protein C).

This text uses material from Wikipedia, licensed under CC BY-SA