Diseases, Conditions, Syndromes

Universal gut microbiome-derived signature predicts cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to ...

Medications

COVID-19: Dexamethasone discovery carries treatment implications

A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effectiveness. ...

Neuroscience

Study examines blood markers, survival in patients with ALS

The blood biomarkers serum albumin and creatinine appear to be associated with survival in patients with amyotrophic lateral sclerosis (ALS) and may help define prognosis in patients after they are diagnosed with the fatal ...

Medical research

Research opens way to significant improvements for medication

International research co-authored by the University of Otago, Christchurch has unraveled a century old scientific mystery, opening the way to significant improvements in the way drugs are delivered to the body.

Diabetes

n-3 PUFA may reduce markers of kidney disease in T2DM

(HealthDay)—In patients with type 2 diabetes and evidence of kidney injury, supplementation with n-3 long-chain polyunsaturated fatty acids (PUFA) does not reduce urine albumin excretion but is associated with a reduction ...

Diabetes

Addition of sotagliflozin for T1DM alters renal hemodynamics

(HealthDay)—Sotagliflozin (SOTA), a dual sodium-glucose cotransporter 1 inhibitor (SGLT1i) and SGLT2i, is associated with short- and long-term renal hemodynamic changes in patients with type 1 diabetes, according to a study ...

Medical research

Here's how your body transports zinc to protect your health

Zinc is essential for wound healing, for vision, for DNA creation, for our senses of taste and smell, even for sexual health. But despite its importance, scientists have never fully understood the mechanism that moves the ...

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