Medical research

Senescent cells may be good when it comes to a bad injury

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases. Now scientists have some of the first evidence that at a younger age at least, ...

Diseases, Conditions, Syndromes

Computer model shows how COVID-19 could lead to runaway inflammation

A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation? The research shows how the molecular structure ...

Medications

Early steroids improve outcomes in patients with septic shock

Some critically ill patients with septic shock need medications called vasopressors to correct dangerously low blood pressure. When high doses of vasopressors are needed or blood pressure isn't responding well, the steroid ...

Diseases, Conditions, Syndromes

Does the COVID-19 cytokine storm exist?

Inflammatory proteins, also known as cytokines, play a crucial role in the immune response. If this immune response is too strong, a phenomenon known as "cytokine storm," it can cause harm to the patient. It has been thought ...

Immunology

The yin and yang of inflammation controlled by a single molecule

Researchers from the Perelman School of Medicine at the University of Pennsylvania have now identified a protein called histone deacetylase 3 (HDAC3) as the orchestrator of the immune system's inflammation response to infection. ...

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