In a landmark study that could lead to new therapies for sickle cell anaemia and other blood disorders, UNSW Sydney-led researchers have used CRISPR gene editing to introduce beneficial natural mutations into blood cells ...
Apr 2, 2018
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ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anemia. She has now developed a promising approach for so-called beta-hemoglobinopathies. ...
Aug 2, 2023
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The ability to precisely edit DNA via CRISPR technology has emerged as the one of the most powerful advances in biology. A new paper showing repair of a genetic mutation in human blood cells represents an important step towards ...
Oct 19, 2016
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Sickle cell disease (SCD) is a form of anemia that is inherited when both parents are carriers of a mutation in the hemoglobin gene. Currently, it can only be diagnosed in pregnancy by carrying out an invasive test that has ...
Jun 17, 2019
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Sickle cell trait and sickle cell disease are risk factors for experiencing kidney function decline among Black individuals. A new study indicates that the risk of acute kidney injury is also higher in adults with sickle ...
Oct 24, 2020
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A team of international researchers has learned that dose escalation of hydroxyurea treatment for children in Uganda with sickle cell anemia is more effective and has similar side effects than a lower fixed dose of the same ...
Jun 24, 2020
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A research study of patients with thalassemia found that low bioavailability of the amino acid arginine may contribute to pulmonary hypertension – increased blood pressure in the pulmonary artery, pulmonary vein or pulmonary ...
Jul 10, 2015
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In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more ...
Apr 30, 2024
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(HealthDay)—An experimental drug may help reduce episodes of pain associated with sickle cell disease, a new study finds.
Dec 5, 2016
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Barely 2 years old, Talia Pisano is getting tough treatment for kidney cancer that spread to her brain. She's also getting a chance at having babies of her own someday.
Aug 11, 2015
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