This week, scientists gathered in Washington, DC for the International Summit on Human Gene Editing to discuss a technology called CRISPR-CAS9, which can insert, remove and change the DNA of basically any organism. It is ...
Dec 4, 2015
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By harnessing the very qualities that make sickle cell disease a lethal blood disorder, a research team led by Duke Medicine and Jenomic, a private cancer research company in Carmel, Calif., has developed a way to deploy ...
Jan 9, 2013
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A gene therapy that could provide a permanent cure for sickle cell disease continues to show success through a third wave of patients, researchers report.
Dec 13, 2021
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A team of researchers from the Broad Institute, Harvard University and St. Jude Children's Research Hospital has used a base editing technique in a novel way to treat sickle cell disease (SCD) in mice. In their paper published ...
A team of UConn biomedical engineers, working with colleagues from Yale, MIT, and Harvard, has developed a simple, inexpensive, and quick technique for the diagnosis and monitoring of sickle cell disease that can be used ...
Oct 23, 2015
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Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared ...
Feb 2, 2023
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Gene therapy trials for sickle cell disease have been showing great promise, even offering hope of a cure. But in early 2021, the trials ground to a halt after reports of blood malignancies in two people in a trial sponsored ...
Feb 15, 2022
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Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults. The finding has implications ...
Oct 12, 2022
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When Lamarcus Jean visits the Hematology Clinic at Dana-Farber/Boston Children's Cancer and Blood Disorders Center, he makes himself right at home. The 6-year-old, whom his mom, Stephanie, describes as "wise beyond his years," ...
Jan 28, 2020
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(HealthDay)—Though heart problems or heatstroke generally are to blame for a young athlete's sudden death, experts now know that carrying an aberration called the sickle cell trait also poses substantial risk.
Dec 28, 2012
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