Genetics

Genome editing at the crossroads of scandal and cure

Genetic modification of babies in China one year ago was universally condemned. At the same time, CRISPR treatments are on their way into our clinics. Jacob Corn explains the difference.

Diseases, Conditions, Syndromes

Transplant beneficial for kidney failure in sickle cell

(HealthDay)—Patients with kidney failure who receive a kidney transplant, including those with sickle cell disease, have lower mortality, according to a study published online Feb. 25 in the Clinical Journal of the American ...

Diseases, Conditions, Syndromes

Sickle cell anemia treatment does not increase malaria risk in Africa

The drug hydroxyurea does not appear to increase the risk of malaria infection in patients with sickle cell anemia who live in malaria-endemic regions, according to a study published online today in Blood, a Journal of the ...

Medical research

No extra mutations in modified stem cells, study finds

The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade. As with any new technology, it brings with it both promise—the hope of fixing ...

Diseases, Conditions, Syndromes

Mapping the global burden of sickle cell anaemia

The first rigorous study to assess the global burden of sickle cell anaemia in recent times is reported today in the Lancet, giving an up-to-date view of the distribution of the disease. Accurate estimates of the numbers ...

Genetics

Archived Guthrie cards find a new purpose

Over the last 50 years, the spotting of newborn's blood onto filter paper for disease screening, called Guthrie cards, has become so routine that since 2000, more than 90% of newborns in the United States have had Guthrie ...

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