Rafal Ciosk and his group at the FMI have identified an important link between the Notch signaling pathway and PRC2-mediated gene silencing. They showed that a fine balance between epigenetic silencing and signaling is crucial ...
Sep 23, 2016
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Researchers at the Institute of Biomedical Research of Bellvitge (IDIBELL), led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction ...
Sep 13, 2016
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Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and proteins that enable prostate ...
Aug 4, 2016
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A new research report appearing in the August 2016 issue of the Journal of Leukocyte Biology reveals a potentially new therapeutic target for preventing or stopping preterm labor. Specifically, using mice, researchers from ...
Aug 1, 2016
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May 5, 2016—A cell-to-cell signaling network that serves as a developmental timer could provide a framework for better understanding the mechanisms underlying human heart valve disease, say University of Oregon scientists.
May 5, 2016
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A pair of molecular signals controls skin and hair color in mice and humans—and could be targeted by new drugs to treat skin pigment disorders like vitiligo, according to a report by scientists at NYU Langone Medical Center.
Apr 28, 2016
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Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in humans. New research shows how the hormone insulin—usually associated with diabetes—is involved in the daily activity ...
Apr 26, 2016
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A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal of Cell Biology. The ...
Apr 6, 2016
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On March 29, Nature Genetics published a research article titled "Genetic lineage tracing identifies endocardial origin of liver vasculature," from Prof. ZHOU Bin's lab at the Institute for Nutritional Sciences (INS), Shanghai ...
Apr 6, 2016
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A new study shows that Frizzled7 (FZD7), a protein present on human breast epithelial cells and a component of the Wnt signaling pathway is uniquely controlled by the Notch signaling pathway, both of which play key roles ...
Apr 5, 2016
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