(Medical Xpress)—A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery ...
Aug 7, 2014
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More than 43,000 American women will die from breast cancer this year. Most of those deaths will occur after the cancer has spread to other organs, a process called metastasis. This involves at least five major steps. Two ...
Aug 18, 2021
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University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according ...
May 23, 2011
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A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice. The findings present new possibilities for treating muscle-wasting conditions associated ...
Feb 23, 2021
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A new research paper titled "Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV" has been published in Aging.
Jan 5, 2023
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Targeted therapy with BRAF-MEK inhibitors is an effective treatment for patients with advanced melanoma that cannot be surgically removed or has spread to other areas of the body. However, many patients become resistant to ...
Sep 2, 2020
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Researchers at The Wistar Institute have found a new way to force cancer cells to self-destruct. Low doses of one anti-cancer drug currently in development, called Gamitrinib, sensitize tumor cells to a second drug, called ...
Apr 19, 2011
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A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against "inflammaging," which is widely believed to be the root cause of many age-related diseases.
Jul 18, 2024
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Intellectual disability due to Fragile X and Down syndromes involves similar molecular pathways report researchers in The EMBO Journal. The two disorders share disturbances in the molecular events that regulate the way nerve ...
Aug 3, 2012
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Desperate for nutrients, rapidly growing pancreatic tumors resort to scavenging "fuel" through an alternative supply route, called macropinocytosis. Scientists are hopeful that blocking this process, often described as "cellular ...
Jun 27, 2019
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