Immunology

How crystals precipitate cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now ...

Medical research

Sendai virus defends against a threat

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription ...

Parkinson's & Movement disorders

Parkinson's disease: Parkin protects from neuronal cell death

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.

Oncology & Cancer

Enzyme offers new therapeutic target for cancer drugs

Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single ...