HIV & AIDS

Developing a new vaccination strategy against AIDS

According to the WHO, there are currently more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million become infected every year. Despite treatment success against the virus, ...

Immunology

In HIV, tissue factor-expressing monocytes trigger coagulation

(HealthDay)—A specific subset of tissue factor (TF)-expressing monocytes persist after virological suppression and trigger the coagulation cascade by activating factor X in HIV, according to a study published online Aug. ...

HIV & AIDS

How long have primates been infected with viruses related to HIV?

Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. ...

Immunology

SIV shrugs off antibodies in vaccinated monkeys

New research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine only needs to stimulate moderate levels of antibodies ...

HIV & AIDS

Novel tool visualizes whole body SIV replication

A collaborative effort between investigators at the Yerkes National Primate Research Center, Emory University School of Medicine and Georgia Institute of Technology has led to the development of a non-invasive method to image ...

HIV & AIDS

New monkey model for AIDS offers promise for medical research

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts – humans and chimpanzees. While this would qualify as good news for most mammals, ...

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