The promise of human organotypic tissues for tissue development, disease modeling, and drug testing is widely recognized, but limitations around cell density, vascular structure, and scale must be solved before that potential ...
Oct 24, 2023
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Skeletal muscle is the largest metabolic organ in the body. It is composed of muscle fibers, blood vessels, nerves and connective tissue. In skeletal muscle, blood vessels are responsible for transporting oxygen, nutrients ...
Oct 24, 2022
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Regular exercise helps prevent and delay the development of type 2 diabetes and its complications. Researchers at Karolinska Institutet, together with a team of international scientists, have discovered that activation of ...
Sep 8, 2022
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Johns Hopkins Medicine researchers recently found a key structural differences in channels that regulate how and when heart and skeletal muscles contract. Identifying the differences between the two, say researchers, provides ...
May 15, 2019
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'Organoids' that mimic the developing spinal cord could assist research and drug development for neurodegenerative diseases such as spinal muscular atrophy and amyotrophic lateral sclerosis.
Mar 18, 2019
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Duchenne muscular dystrophy (DMD) is a devastating genetic disease that impairs cardiac and skeletal muscle development. People with DMD gradually lose ambulation in childhood, acquire respiratory and heart failure in young ...
Aug 30, 2018
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An immobile mutant zebrafish first described by scientists more than 20 years ago turns out to have defects in the same gene as people with a rare muscle-degenerating disorder called nemaline myopathy, an A*STAR study has ...
Oct 19, 2017
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Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a ...
Aug 22, 2017
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Skeletal muscles are built from small contractile units, the sarcomeres. Many of these sarcomeres are connected in a well-ordered series to form myofibrils that span from one muscle end to the other. Contractions of these ...
Mar 14, 2014
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Skeletal muscle has proved to be very difficult to grow in patients with muscular dystrophy and other disorders that degrade and weaken muscle. Researchers at Boston Children's Hospital's Stem Cell Program now report boosting ...
Nov 7, 2013
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