Of the 198 new oncology drugs approved by the U.S. Food and Drug Administration (FDA) between 1998 and 2022, approximately 43% were precision oncology therapies, the use of which is guided by biomarker testing.
Oct 18, 2023
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Scientists have shown exactly how mutations in two different genes coordinate to drive the development of malignant lung tumors, according to a new report in the open-access journal eLife.
Aug 27, 2019
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Hesperos Inc., pioneers of the "human-on-a-chip" in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules ...
Jul 3, 2019
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A new combination of drugs that may have the potential to treat a type of leukemia has been uncovered by a detailed molecular examination of leukemia cells by RIKEN researchers1.
Jun 28, 2021
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Scientists have for the first time revealed the structure surrounding important receptors in the brain's hippocampus, the seat of memory and learning.
May 12, 2021
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The mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed. Investigators at Cedars-Sinai have found that inflammatory bowel disease (IBD) patients with higher levels ...
Jul 25, 2023
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Microglia are cells that are central to both brain health as well as disease progression in many neurological conditions. Normally, microglia stabilize the brain by clearing out damaged neurons and protein plaques often associated ...
Jan 25, 2023
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Crohn's disease, a type of inflammatory bowel disease, has no cure. But there are many treatments, specific to type, and it is possible to keep the symptoms under control.
May 8, 2023
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Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically increases the ...
Dec 21, 2012
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A new research perspective titled "Using cancer proteomics data to identify gene candidates for therapeutic targeting" has been published in Oncotarget.
May 10, 2023
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