What makes the vital layer of protective cells around the brain and spinal cord—the blood-brain barrier—more or less permeable has been one of the more mystifying questions in neuroscience.
Jul 13, 2023
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Relapses in a common form of leukemia may be preventable following new research that has identified how the cancer develops resistance to first line treatments.
Apr 9, 2024
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There are hundreds of metabolic disorders—including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria. These disorders lead to congenital diseases that produce a critical enzyme deficiency that ...
Jan 16, 2019
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Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs. This work opens up the prospect of developing a new ...
Apr 16, 2019
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In order to sustain fast growth, cancer cells need to take up nutrients at a faster rate than healthy cells. The human glutamine transporter ASCT2 allows the amino acid glutamine to enter cells and is upregulated in many ...
Jul 31, 2019
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Scientists have identified two small molecules that could be pursued as potential treatments for chronic inflammatory diseases. According to a paper published in PLOS Computational Biology, the researchers singled out the ...
Apr 20, 2017
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Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published ...
Mar 5, 2013
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Researchers have identified a protein that, when targeted, enables cisplatin-resistant cancer cells to become responsive to treatment. Cisplatin, and other similar platinum drugs, are incredibly effective at killing rapidly ...
Mar 27, 2024
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Vaccination, masks and physical distancing help limit the spread of COVID-19—but, researchers say, the disease is still going to infect people, and doctors are still going to need better medicines to treat patients. This ...
Apr 15, 2021
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Traditionally, therapies combining DNA-damaging agents and STING agonists have shown potential in treating cancer by enhancing immune response and reshaping the tumor microenvironment. However, until now, creating a single ...
Mar 20, 2024
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