Scripps Research Institute scientists have discovered new elements of the blood clot-formation process. The findings could lead to better drugs for preventing heart attacks and other clot-related conditions.
Jun 13, 2011
0
0
Close to 70 percent of men with erectile dysfunction (ED) respond to the ED drug sildenafil. However, only about 50 percent of men with diabetes—a population commonly affected by ED—achieve positive results with sildenafil. ...
Sep 7, 2017
0
0
A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s—with normal cholesterol levels and no other risk factors—to develop coronary artery disease has been identified, ...
Jul 7, 2023
0
44
The majority of drugs used to treat asthma today are the same ones that were used 50 years ago. New drugs are urgently needed to treat this chronic respiratory disease, which causes nearly 25 million people in the United ...
Sep 23, 2014
0
0
Scientists at the Gladstone Institutes have discovered how to make a new type of cell that is in between embryonic stem cells and adult heart cells, and that may hold the key to treating heart disease. These induced expandable ...
Mar 3, 2016
0
10
New research reveals that insulin applied in therapeutic doses selectively stimulates the formation of new elastic fibers in cultures of human aortic smooth muscle cells. These results advance the understanding of the molecular ...
Jan 9, 2012
0
0
Scientists have implicated a type of stem cell in the calcification of blood vessels that is common in patients with chronic kidney disease. The research will guide future studies into ways to block minerals from building ...
Sep 8, 2016
0
130
Oxidized lipids are known to play a key role in inflaming blood vessels and hardening arteries, which causes diseases like atherosclerosis. A new study at UCLA demonstrates that they may also contribute to pulmonary hypertension, ...
Aug 27, 2014
0
0
The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering studies ...
Sep 7, 2012
0
0
Many questions remain about the mechanisms that control blood pressure, particularly in relation to hypertension. Among the factors involved in regulation of blood vessel behavior, the apelin receptor (APJ) has been presumed ...
Nov 1, 2019
0
3
