Medical research

Targeting ion channels to manage osteoarthritis pain

Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy to manage osteoarthritis pain, according to a Northwestern Medicine study published in Cell Reports.

Medications

Building a better painkiller

In recent years, cannabidiol, a compound derived from cannabis plants, has begun popping up more and more in everyday life. Now legal in most U.S. states, the cannabinoid commonly known as CBD can be found in supermarkets ...

Genetics

New genetic risk factors for arrhythmia discovered

A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.

Neuroscience

AAN issues guideline for treatment of painful diabetic neuropathy

Diabetic neuropathy refers to nerve damage due to diabetes and it may lead to pain and numbness, most often in the hands and feet. To help neurologists and other doctors determine the best treatment for people with diabetic ...

Neuroscience

Rare form of autism exhales secrets of breathing

Breathing difficulties mark a rare form of autism. Now, UConn researchers have traced the symptom to a specific set of brain cells—and possibly found a way to help sufferers.

Biomedical technology

Mimicking nature to provide long-lasting local anesthesia

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties. They provide pain relief without toxic effects on local nerves and muscles, and are an ...

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