Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy to manage osteoarthritis pain, according to a Northwestern Medicine study published in Cell Reports.
Oct 5, 2022
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(HealthDay)—Blockade of voltage-gated sodium channels (NaChs) in pancreatic α cells has anti-diabetic effects, according to research published online May 8 in Diabetes.
May 15, 2014
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Using computer models and laboratory rats, Johns Hopkins researchers have demonstrated that "direct electrical current" can be delivered to nerves preferentially, blocking pain signals while leaving other sensations undisturbed.
Apr 18, 2018
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A new stem cell-based approach to studying epilepsy has yielded a surprising discovery about what causes one form of the disease, and may help in the search for better medicines to treat all kinds of seizure disorders.
Jul 25, 2013
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A heartbeat is a carefully coordinated series of electrical signals led by sodium ion channels, which tell the heart when to contract and to relax. Any disruption to these signals may lead to cardiac diseases such as an irregular ...
Apr 3, 2023
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It has been 60 years since scientists discovered that sodium channels create the electrical impulses crucial to the function of nerve, brain, and heart cells—all of which are termed "excitable." Now researchers at Yale ...
Oct 17, 2013
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An investigation into the molecular causes of a debilitating condition known as "Man on Fire Syndrome" has led Yale researchers to develop a strategy that may lead to personalized pain therapy and predict which chronic pain ...
Nov 13, 2012
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University of Queensland researchers have identified a unique pain pathway targeted by a notorious Australian stinging tree and say it could point the way to new, non-opioid pain relief.
May 4, 2023
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The compound huperzine A can increase resistance to induced seizures in mouse models of genetic epilepsy, scientists at Emory University School of Medicine have found.
Nov 10, 2016
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Breathing difficulties mark a rare form of autism. Now, UConn researchers have traced the symptom to a specific set of brain cells—and possibly found a way to help sufferers.
Oct 13, 2021
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