Oncology & Cancer
Hedgehog signaling pathway key in treating osteosarcoma: Study
The strangely named hedgehog pathway that's crucial to bone growth has emerged as a key in the fight to treat the bone cancer osteosarcoma.
Nov 28, 2023
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News tagged with sonic hedgehog pathway
Medications
Epilepsy drug inhibits brain tumor development
Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumors. A specific mTOR inhibitor has the ability to cross the blood-brain barrier to both reach and attack ...
Nov 29, 2019
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Oncology & Cancer
Researchers identify possible approach to block medulloblastoma growth
University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.
Oct 24, 2019
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Medical research
Researchers regrow hair on wounded skin
By stirring crosstalk among skin cells that form the roots of hair, researchers report they have regrown hair strands on damaged skin. The findings better explain why hair does not normally grow on wounded skin, and may help ...
Nov 28, 2018
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Oncology & Cancer
Study helps explain launch switch for most common malignant pediatric brain tumor
A delicate balance during brain development could have profound implications for understanding and treating medulloblastoma, the most common malignant brain tumor affecting children.
Mar 29, 2018
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Oncology & Cancer
Atoh1, a potential Achilles' heel of Sonic Hedgehog medulloblastoma
Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation ...
Dec 12, 2017
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Oncology & Cancer
New pathway identified as a target for precision medicine against a common brain tumor
St. Jude Children's Research Hospital scientists have discovered a promising target for precision medicines to block a mechanism that drives several cancers, including about 30 percent of cases of the brain tumor called medulloblastoma. ...
Nov 2, 2017
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Oncology & Cancer
Genomic analysis of liver cancer reveals unexpected genetic players
Liver cancer has the second-highest worldwide cancer mortality, and yet there are limited therapeutic options to manage the disease. To learn more about the genetic causes of this cancer, and to identify potential new therapeutic ...
Jun 16, 2017
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Genetics
New role for hedgehog gene offers better understanding of lung disease
The whimsically named sonic hedgehog gene, best known for controlling embryonic development, also maintains the normal physiological state and repair process of an adult healthy lung, if damaged, according to new research ...
Oct 5, 2015
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Medical research
Experimental cancer drug shows therapeutic promise in mouse models of multiple sclerosis
An experimental drug originally identified in a National Cancer Institute library of chemical compounds as a potential therapy for brain and basal cell cancers improves the symptoms of mice with a form of the debilitating ...
Sep 30, 2015
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