Mutations in a gene known as interferon regulatory factor 6 (IRF6) that cause cleft lip and palate also are implicated in neural tube defects such as spina bifida, suggests research by an international study team published ...
Jan 25, 2019
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A Michigan Medicine study finds that people with two pediatric-onset neurodevelopmental disorders are prescribed opioids at significantly higher rates than those without the conditions, raising concerns over addiction, overdose ...
Jul 7, 2022
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A team of specialists at UPMC Magee-Womens Hospital and UPMC Children's Hospital of Pittsburgh have performed UPMC's first in-utero surgery to close an open neural tube defect in a baby months before her birth.
Jun 3, 2019
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The latest and final in a series of congressionally mandated biennial reviews of the evidence of health problems that may be linked to exposure to Agent Orange and other herbicides used during the Vietnam War changed the ...
Mar 10, 2016
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Children with a severe type of spina bifida called myelomeningocele have a high prevalence of obesity and excess fat accumulation in their lower extremities. In a study designed to assess bone, muscle and fat tissue distribution ...
Mar 14, 2016
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Spina bifida (myelomeningocele) is the most common, permanently disabling birth defect compatible with life. In a collection of articles, published in the Journal of Pediatric Rehabilitation Medicine, experts describe important ...
Feb 28, 2019
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Valproic acid—a drug used to treat epilepsy, migraine, and bipolar disorder—can cause birth defects when taken during pregnancy. Now, a study publishing June 14 in the open access journal PLOS Biology by Bill Keyes of ...
Jun 14, 2022
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Jessica Lingor remembers the crisp December day nearly six years ago when doctors diagnosed her yet-to-be-born daughter, Kaylie, with spina bifida—a type of birth defect in which a baby's spinal cord fails to develop or ...
Oct 1, 2021
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Researchers on the path to finding a cure for spina bifida have identified specific elements in stem cell secretions as key to protecting neurons and ultimately reducing the lower-limb paralysis associated with the birth ...
Mar 7, 2019
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Mary R. Loeken, Ph.D., Investigator in the Section on Islet Cell and Regenerative Biology at Joslin Diabetes Center and Associate Professor of Medicine at Harvard Medical School, has discovered a molecular pathway responsible ...
Nov 6, 2014
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