Oncology & Cancer

Protein AKAP8 suppresses breast cancer metastasis

A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, ...

Oncology & Cancer

Splicing factor to blame in triple negative breast cancer

If your DNA is a cookbook, a single gene is a recipe. But it's a flexible recipe that if edited one way can make a pie; edited another way can make a cake. And that difference can mean cancer, as a team of researchers who ...

Neuroscience

Tau-mediated RNA splicing errors linked to Alzheimer's disease

A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer's disease. The study, led by researchers at Baylor College of Medicine and the ...

Oncology & Cancer

New way to target cancer's diversity and evolution

Scientists have revealed close-up details of a vital molecule involved in the mix and match of genetic information within cells—opening up the potential to target proteins of this family to combat cancer's diversity and ...

Neuroscience

A match made in neural heaven: How a neuron grows an axon

While the neural architecture responsible for the transmission of electrical impulses has been known for more than a century, the basic biology behind how a neuron acquires its one and only axon—a fundamental component ...

Genetics

Unraveling a genetic network linked to autism

Donnelly Centre researchers have uncovered a genetic network linked to autism. The findings, described in the journal Molecular Cell, will facilitate developing new therapies for this common neurological disorder.

Genetics

Predicting how splicing errors impact disease risk

No one knows how many times in a day, or even an hour, the trillions of cells in our body need to make proteins. But we do know that it's going on all the time, on a massive scale. We also know that every time this happens, ...

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