Medical research
Key aspects of human cell aging reversed by new compounds
Key aspects of the ageing of human cells can be reversed by new compounds developed at the University of Exeter, research shows.
Aug 7, 2018
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Page 4 - News tagged with splicing
HIV & AIDS
Discovery of how HIV hedges its bets opens the door to new therapies
A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or ...
May 10, 2018
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Neuroscience
Better understanding amyotrophic lateral sclerosis by looking at how cells change
It took eight long years of research, but now an international team led by neuroscientists at Université de Montréal has discovered a basic molecular mechanism that better helps understand how Lou Gehrig's disease, or amyotrophic ...
Mar 19, 2018
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Medical research
Old human cells rejuvenated in breakthrough discovery on ageing
A team led by Professor Lorna Harries, Professor of Molecular Genetics at the University of Exeter, has discovered a new way to rejuvenate inactive senescent cells. Within hours of treatment the older cells started to divide, ...
Nov 7, 2017
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Oncology & Cancer
Biologists identify possible new strategy for halting brain tumors
MIT biologists have discovered a fundamental mechanism that helps brain tumors called glioblastomas grow aggressively. After blocking this mechanism in mice, the researchers were able to halt tumor growth.
Sep 29, 2017
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Oncology & Cancer
Alternative splicing, an important mechanism for cancer
Cancer, which is one of the leading causes of death worldwide, arises from the disruption of essential mechanisms of the normal cell life cycle, such as replication control, DNA repair and cell death. Thanks to the advances ...
Sep 22, 2017
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Oncology & Cancer
How a non-coding RNA encourages cancer growth and metastasis
A mechanism that pushes a certain gene to produce a non-coding form of RNA instead of its protein-coding alternative can promote the growth of cancer, report researchers at the Medical University of South Carolina (MUSC) ...
Aug 21, 2017
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Medical research
Change in protein production essential to muscle function
Researchers at Baylor College of Medicine have shed light on the process that guides the maturation of newborn muscles into adult, fully functional organs. In mice, they determined that a group of genes involved in calcium ...
Aug 14, 2017
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Neuroscience
New study reveals how RNA splicing errors may spark the development of both ALS and a form of dementia
The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)—rare and related neurological disorders marked by progressive deterioration of motor or cognitive abilities—may ...
Jun 13, 2017
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Genetics
Assay of nearly 5,000 mutations reveals roots of genetic splicing errors
It's not so hard anymore to find genetic variations in patients, said Brown University genomics expert William Fairbrother, but it remains difficult to understand whether and how those mutations undermine health.
Apr 17, 2017
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