A team of researchers at the University of Michigan Health Rogel Cancer Center has designed a molecule that impairs signaling mediated by two key drivers of cancer therapy resistance. The design and preclinical evaluation ...
Jul 29, 2024
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Some genes are known to drive cancer, and astonishing new research shows why: Mutations in the noncoding regions become functional, altering the abundance of messenger RNA, or mRNA, and potentially facilitating cell proliferation. ...
Apr 18, 2024
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Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer ...
Mar 7, 2024
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Researchers at the University of Colorado Anschutz Medical Campus studying interactions between nerves and tumor microenvironments have found that commonly used drugs like botox may stop or slow the progression of certain ...
Feb 28, 2024
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Lidocaine—often used as a numbing agent for outpatient medical procedures—activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman ...
Nov 22, 2023
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Scientists from Queen Mary University of London have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive ...
Sep 4, 2023
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Equipping cancer-infecting (oncolytic) viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study in ...
Aug 14, 2023
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A new study has shown how, on average, people in the UK have facial skin that is far more DNA damaged from the sun than people in Singapore, explaining the far higher risk of developing the most common skin cancers in the ...
Aug 3, 2023
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Cases of human papillomavirus (HPV)-associated cancers of the head and neck, known as head and neck squamous cell carcinoma (HNSCC), are rapidly increasing throughout the United States. Unfortunately, relatively little is ...
Jul 31, 2023
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Early on, every stem cell faces a fateful choice. During skin development, for instance, the embryonic epidermis begins as a single layer of epidermal progenitor cells. Their choice is to become a mature epidermal cell or ...
Jul 28, 2023
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In medicine, squamous cell carcinoma (SCC) is a form of cancer of the carcinoma type that may occur in many different organs, including the skin, lips, mouth, esophagus, urinary bladder, prostate, lungs, vagina, and cervix. It is a malignant tumor of squamous epithelium (epithelium that shows squamous cell differentiation).
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