A combination of six antibodies can successfully prepare mice to accept blood and immune stem cells from an immunologically mismatched donor, according to a study by researchers at the Stanford University School of Medicine.
Jun 13, 2019
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Babies born prematurely often face intense medical challenges, including intestines that are underdeveloped or diseased. While an intestine transplant can benefit some patients, many babies are simply too small to endure ...
Jun 7, 2019
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Researchers at Stanford and the University of Tokyo may have cracked the code to doing stem cell transplants and gene therapy without radiation and chemotherapy.
May 30, 2019
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A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting immune cells do not develop ...
Apr 17, 2019
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In preclinical trials, Stanford scientists and their collaborators harnessed the gene-editing system CRISPR-Cas9 to replace the mutated gene underpinning the devastating immune disease.
Apr 11, 2019
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Scientists at Winship Cancer Institute of Emory University, Children's Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells' stiffness could possibly facilitate mobilization procedures ...
Mar 19, 2019
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The University of Minnesota Medical School continues its legacy of advancing cell replacement therapies with a scientific breakthrough that highlights the promise of cell therapies for muscular dystrophy.
Feb 14, 2019
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Blood stem cell transplants—also known as bone-marrow transplants—can cure many blood, immune, autoimmune, and metabolic disorders, from leukemia to sickle-cell disease. But to make sure the healthy blood cells "take," ...
Feb 8, 2019
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Functional B-1 cells derived from mouse embryonic stem cells are capable of long-term engraftment and secrete natural antibodies after transplantation in mice, researchers report February 7th in the journal Stem Cell Reports. ...
Feb 7, 2019
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In a study with significant implications for human organ transplantation, researchers have successfully grown functional mouse kidneys inside rats from just a few donor stem cells.
Feb 5, 2019
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