In almost every mammalian cell, you will find the endoplasmic reticulum, a network of continuous membranes responsible for controlling metabolism as well as the folding, assembly and secretion of proteins. Since the endoplasmic ...
Mar 10, 2016
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Pulling an "all-nighter" before a big test is practically a rite of passage in college. Usually, it's no problem: You stay up all night, take the test, and then crash, rapidly catching up on lost sleep. But as we age, sleep ...
Feb 20, 2014
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A brain pathway that is stimulated by traumatic or fearful experiences can be disrupted by two compounds that show promise for preventing post-traumatic stress disorder, Indiana University researchers reported.
Oct 15, 2012
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Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure – a leading cause of ...
Aug 1, 2013
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Testosterone, the primary male sex hormone, appears to have antidepressant properties, but the exact mechanisms underlying its effects have remained unclear. Nicole Carrier and Mohamed Kabbaj, scientists at Florida State ...
Apr 2, 2012
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Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. ...
Mar 7, 2018
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Scientists have identified a new therapeutic strategy for treating a very aggressive form of breast cancer.
Oct 15, 2018
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Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology. ...
May 8, 2019
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Researchers at The Wistar Institute and collaborators from the University of Notre Dame are developing anticancer compounds targeting a pathway of the endoplasmic reticulum (ER) stress response implicated in the development ...
Oct 13, 2020
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An innovative screening technology that tags compounds with unique strands of DNA – like barcodes – will be used to assess up to a billion prototype drug molecules for anti-cancer activity, under a collaboration announced ...
Jan 22, 2014
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