Medical research
At last, a reason why stress causes DNA damage
For years, researchers have published papers that associate chronic stress with chromosomal damage.
Aug 21, 2011
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News tagged with stress response pathway
Oncology & Cancer
New gene implicated in cancer, cellular stress response
Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity, according to findings published in Nature Communications.
Feb 21, 2023
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Oncology & Cancer
Why don't T cells destroy solid tumors during immunotherapy?
The great hope of cancer immunotherapy is to bolster our own immune cells in specific ways to keep cancer cells from evading our immune system. Although much progress has been made, immunotherapy does not always work well. ...
Dec 19, 2022
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Psychology & Psychiatry
Scientists develop new method that predicts vulnerability to stress
Stress is part of life for everyone, but how we respond to it seems to vary from person to person. For some, the effects of a stressful situation can be long-lasting and lead to anxiety, depression, and other health problems; ...
Dec 17, 2019
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Psychology & Psychiatry
Neural circuits underlying a psychotherapeutic regimen for fear disorders
While visually tracking a moving light swinging side to side, a person's attention is naturally diverted to that movement, and what was previously in their mind is placed to the side. This alternating bilateral sensory stimulation ...
Feb 14, 2019
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Medical research
Signaling pathway involving the Golgi apparatus identified in cells with Huntington's disease
Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. ...
Mar 7, 2018
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Oncology & Cancer
New drug stalls estrogen receptor-positive cancer cell growth and shrinks tumors
An experimental drug rapidly shrinks most tumors in a mouse model of human breast cancer, researchers report in the Proceedings of the National Academy of Sciences. When mice were treated with the experimental drug, BHPI, ...
Mar 30, 2015
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Neuroscience
Blood pressure drug protects against symptoms of multiple sclerosis in animal models
An FDA-approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study. The drug appears to enhance an innate cellular ...
Mar 13, 2015
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Medical research
Scientists uncover new, fundamental mechanism for how resveratrol provides health benefits
Scientists at The Scripps Research Institute (TSRI) have found that resveratrol, the red-wine ingredient once touted as an elixir of youth, powerfully activates an evolutionarily ancient stress response in human cells. The ...
Dec 22, 2014
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Medical research
Study in fruitflies strengthens connection among protein misfolding, sleep loss, and age
Pulling an "all-nighter" before a big test is practically a rite of passage in college. Usually, it's no problem: You stay up all night, take the test, and then crash, rapidly catching up on lost sleep. But as we age, sleep ...
Feb 20, 2014
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