On diagnosis of acute myeloid leukemia, the mesenchymal stem cells (MSCs) in bone marrow often show alterations in gene and protein expression, proliferation capacity, and function, but whether these are a cause or result ...
May 4, 2017
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One reason pancreatic cancer has a particularly low survival rate is the difficulty in getting drugs to the tumour, but new knowledge of how pancreatic cancer cells invade neighbouring cells could change that.
Mar 29, 2017
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An international research team led by the University of Michigan Life Sciences Institute is changing the understanding of the key cellular and molecular events that trigger graft-versus-host disease, an often fatal complication ...
Mar 20, 2017
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Just as an invasive weed might need nutrient-rich soil and water to grow, many cancers rely on the right surroundings in the body to thrive. A tumor's microenvironment—the nearby tissues, immune cells, blood vessels and ...
Jan 19, 2017
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A new study demonstrates that non-blood cell forming stem cells present in human bone marrow play an important role in maintaining the hematopoietic microenvironment, and these stromal cells appear to retain full self-renewal ...
Nov 9, 2016
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The inside of our small intestine teems with microbes – our gut microbiome – while just across a thin barrier, the immune system patrols and prepares for battle.
Nov 3, 2016
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AIM, within the Institute for Basic Science (IBS), published an intriguing paper in Scientific Reports, on August 2, detailing a novel explanation to a problem known to immunologists for decades: What causes the decline in ...
Aug 2, 2016
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For the first time, researchers have discovered that some leukemia cells harvest energy resources from normal cells during chemotherapy, helping the cancer cells not only to survive, but actually thrive, after treatment.
Jun 2, 2016
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The addition of high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London (QMUL). The promising initial results ...
May 24, 2016
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In order to fight invading pathogens, the immune system uses "outposts" throughout the body, called lymph nodes. These are small, centimeter-long organs that filter fluids, get rid of waste materials, and trap pathogens, ...
May 5, 2016
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