In a largely neglected brain region, scientists identified neurons that produce the stress hormone CRH (corticotropin-releasing hormone). They showed that the CRH produced in this region plays a role in behavioral arousal, ...
Nov 25, 2022
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Northwestern Medicine investigators have discovered that dopaminergic neurons in the substantia nigra utilize a specific ion channel to meet anticipated energy needs, according to findings published in Science Advances.
Oct 20, 2022
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Scientists have uncovered how dopamine connects subregions of the striatum essential for habit formation, according to a Northwestern Medicine study published in Cell Reports, findings that may change the overall understanding ...
Aug 25, 2022
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36
A team of researchers affiliated with several institutions in the U.S. has identified a subtype of brain cells that die in Parkinson's patients. In their study, published in the journal Nature Neuroscience, the group used ...
A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9 in the open-access journal ...
Mar 22, 2022
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Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.
Dec 13, 2021
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In late-stage Parkinson's disease, the drug levodopa becomes less effective in treating symptoms because of the inexorable loss of dopamine-releasing neurons. But a new Northwestern Medicine preclinical study shows a gene ...
Nov 3, 2021
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The neurotransmitter dopamine influences the activity of a wide variety of brain areas. A deficiency of this substance can have drastic consequences: The death of dopamine-producing nerve cells in the substantia nigra—a ...
Sep 14, 2021
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35
A growing body of research has shown that misshapen and misfolded alpha-synuclein, the protein culprit behind Parkinson's disease and its characteristics, travels from the gut to the brain, where it spreads and sticks together ...
Jan 5, 2021
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Since the coronavirus pandemic began in the spring, many people have only seen their close friends and loved ones during video calls, if at all. A new study from MIT finds that the longings we feel during this kind of social ...
Nov 23, 2020
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