Tumor suppressor genes protect cells from malignant transformation. If they are turned off as a result of chemical modifications in DNA, called epigenetic labels, this contributes to the development of cancer. As opposed ...
Jun 12, 2017
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Cells are constantly turning proteins on and off via molecular switches—phosphate molecules—that have become common drug targets. in a new study, lung cancer tumors were prevented in mice by a novel small molecule that ...
May 16, 2017
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The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich led by Professor Heiko Hermeking have now ...
May 11, 2017
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A protein that typically helps keep cells organized and on task becomes a tumor suppressor in the face of liver cancer, scientists say.
May 8, 2017
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Every time a cell divides, there is a chance for a mutation (mistake) to occur in the DNA - the substance that carries genetic information in all living organisms. These mutations can lead to cancer.
May 1, 2017
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Germinal centers are transient structures in the lymph nodes where antibody-producing B cells proliferate and differentiate at extraordinary rates. Germinal centers can be visually divided into a dark zone and light zone. ...
Apr 19, 2017
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Myelodysplastic syndrome is an umbrella term used to describe disorders characterized by the bone marrow's inability to produce normal blood cells. Researchers from Charité - Universitätsmedizin Berlin have found that a ...
Apr 12, 2017
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Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that p300, a protein that increases gene expression by attaching acetyl molecules to DNA, may stop myelodysplastic ...
Mar 27, 2017
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A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program—it can emphasize or silence genes. The new research shows that if epigenetics is disrupted, it might ...
Mar 24, 2017
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Genetic mutations that cause cancer also weaken cancer cells, creating an opportunity for researchers to develop drugs that will selectively kill them, while sparing normal cells. This concept is called "synthetic lethality" ...
Mar 20, 2017
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