Cells with too few or too many chromosomes have long been known to be a hallmark of cancer — but the cause of this abnormal number of chromosomes has been little understood. Now, in the August 19th issue of Science, ...
Aug 18, 2011
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Researchers have identified a protein long known to regulate gene expression as a potent suppressor of breast cancer growth. Their study, in the journal Oncogene, is the first to demonstrate how this protein, known as Runx3, ...
Jun 27, 2011
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University of Minnesota Medical School researchers have discovered a method to quickly and exponentially grow regulatory T-cells – also known as "suppressor cells." The new process enables replication of the cells by ...
May 18, 2011
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An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development ...
May 16, 2011
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A gene thought to be associated with cancer development can be a tumor suppressor gene in mice, researchers have discovered. Understanding which genes are involved in spreading cancer could lead to future therapies.
Apr 11, 2011
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Receptor protein tyrosine phosphatases are cell membrane-localized proteins. They are regulators of cell-cell contacts and are also considered likely to be tumor suppressors, but the specifics of how they function are unknown. ...
Jul 24, 2024
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There are many anti-cancer genes that are no longer active in human tumors, preventing them from carrying out their protective function against cell transformation. One of the main mechanisms used by cancer cells to silence ...
Mar 14, 2024
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Epithelioid sarcoma, a rare aggressive cancer that usually strikes young adults, and rhabdoid tumors, which affect children, have long been difficult to treat. But the outlook for people with these subtypes of soft tissue ...
Feb 5, 2024
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Researchers at Kanazawa University report in Cancer Research how Kras and p53 mutations influence the tumor suppressor and promoter functions of a TGF- ß pathway. The findings may lead to a new approach for colorectal cancer ...
Nov 29, 2023
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The strangely named hedgehog pathway that's crucial to bone growth has emerged as a key in the fight to treat the bone cancer osteosarcoma.
Nov 28, 2023
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