(Medical Xpress)—The hormone progesterone could become part of therapy against the most aggressive form of brain cancer. High concentrations of progesterone kill glioblastoma cells and inhibit tumor growth when the tumors ...
Jun 19, 2014
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(Medical Xpress)—Illinois Institute of Technology researcher Jialing Xiang, who recently discovered Baxdelta2, the powerful tumor suppressor found only in mutated cells, has learned more about its cell death-causing mechanism ...
Jun 12, 2014
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Scientists armed with a supercomputer and a vast trove of newly collected data on the body's most potent "tumor suppressor" gene have created the best map yet of how the gene works, an accomplishment that could lead to new ...
May 27, 2014
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Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects ...
Apr 10, 2014
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A team headed by Angel R. Nebreda at the Institute for Research in Biomedicine (IRB) identifies a dual role of the p38 protein in colon cancer. The study demonstrates that, on the one hand, p38 is important for the optimal ...
Mar 27, 2014
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The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive. Sometimes oncogenes manage to initiate tumor development ...
Mar 24, 2014
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Northwestern Medicine scientists have demonstrated that cancer cells – and not normal cells – can be killed by eliminating either the FAS receptor, also known as CD95, or its binding component, CD95 ligand.
Mar 21, 2014
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Cancer cells have long been known to have higher rates of the energy-generating metabolic pathway known as glycolysis. This enhanced glycolysis, a phenomenon known as the Warburg effect, is thought to allow cancer cells to ...
Feb 24, 2014
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Pancreas cancer is notoriously impervious to treatment and resists both chemotherapy and radiotherapy. It has also been thought to provide few targets for immune cells, allowing tumors to grow unchecked. But new research ...
Feb 20, 2014
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One of the hopes for victory against cancer hinges on naturally-occurring proteins whose job is to make their host cell die.
Feb 3, 2014
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