Genetics

'CYCLOPS' genes may serve as an Achilles' heel in tumor cells

BOSTON--The genomic tumult within tumor cells has provided scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard with clues to an entirely new class of genes that may serve as an Achilles' ...

Medical research

Rat study shows chrysotile asbestos is strong carcinogen

(HealthDay) -- Chrysotile, a commercially used type of asbestos, induces malignant mesothelioma (MM) in the rat peritoneal cavity, with pathogenesis strongly linked to iron overload, according to a study published online ...

Oncology & Cancer

Normal gene hinders breast cancer chemotherapy

Presence of normal p53, a tumor suppressor gene, instead of a mutated version, makes breast cancer chemotherapy with doxorubicin less effective. The preclinical study led by MD Anderson scientists was published today in the ...

Oncology & Cancer

Outwitting a brainy gene

(Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller ...

Oncology & Cancer

Therapy exploits 'addiction' of leukemia cells

A new study describes a therapeutic approach to halting cancer progression by exploiting a previously unrecognized "addiction" of leukemia cells to specific signaling molecules. The research, published by Cell Press online ...

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