Immunology

Proteins team up to turn on T cells

The fates of various cells in our bodies—whether they become skin or another type of tissue, for example—are controlled by genetic switches. In a new study, Caltech scientists investigate the switch for T cells, which ...

Genetics

Cancer-preventing protein finds its own way in our DNA

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair ...

Oncology & Cancer

'Master switch' helps cancer cells survive stress

Scientists have discovered a 'master switch' within cancer cells that seems to override the normal stress response and allows them to survive conditions that would normally be lethal.

Genetics

Research shows hope for personalized genome sequencing

Imagine if you could carry a credit card-size record of all the 3 billion A's, T's C's, and G's that make up the alphabet soup of your genome. A simple swipe of the card could inform your physician right away if a drug being ...

Medical research

Photopharmacology: Optical control of insulin secretion

Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have chemically modified an anti-diabetic agent so as to make its action dependent on light. The resulting prototype compound, termed JB253, induces release of ...

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