New research from the University of California, Irvine reveals that sex differences in learning and memory mechanisms are triggered by biological events occurring during puberty. Findings show prepubescent female rodents ...
Feb 9, 2022
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As we live in a dynamically changing environment, it is important for our brain to not only learn new things but also to modify existing memories. This is commonly referred to as "cognitive flexibility." Without this ability, ...
Dec 21, 2021
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The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be ...
Nov 29, 2021
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Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.
Sep 16, 2021
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Building on recent research confirming how ketamine induces rapid antidepressant action, Professor of Pharmacology Lisa Monteggia and her collaborators show how the molecular mechanism of the gene MeCP2 and associated synaptic ...
Jul 28, 2021
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New research in rats suggests a common antioxidant supplement may protect the next generation from a leading cause of blindness stemming from a high-sugar diet during pregnancy. The study is published ahead of print in the ...
May 21, 2021
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In neurons, changes in the size of dendritic spines—small cellular protrusions involved in synaptic transmission—are thought to be a key mechanism underlying learning and memory. However, the specific way in which these ...
May 18, 2021
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Information flows in a well-defined direction in the brain: Chemical and electrical signals are passed from one neuron to the other across the synapse, from the pre-synaptic to the post-synaptic neuron. Now, Peter Jonas and ...
May 18, 2021
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The cerebellum—a part of the brain once recognized mainly for its role in coordinating movement—underwent evolutionary changes that may have contributed to human culture, language and tool use. This new finding appears ...
May 6, 2021
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Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer's disease (AD), a key step toward eventually ...
May 5, 2021
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