Among the confounding challenges of diagnosing and treating Alzheimer's disease (AD) is the fact that patients with asymptomatic and symptomatic versions of the degenerative condition may share similar neuropathological burdens ...
Jul 24, 2019
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The contact areas between nerve cells are called synapses. What happens there lies at the heart of communication between nerve cells. Communication starts with the release of chemical messengers known as neurotransmitters ...
Sep 4, 2017
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Information flows in a well-defined direction in the brain: Chemical and electrical signals are passed from one neuron to the other across the synapse, from the pre-synaptic to the post-synaptic neuron. Now, Peter Jonas and ...
May 18, 2021
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Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders. Every year, new genetic mutations or protein dysregulations are identified as potential ...
Jan 4, 2024
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Synapses are the power junctions that allow living creatures to function. Popularly associated with learning and memory, they play a more fundamental role in our existence by regulating everything from breathing, sleeping ...
Aug 15, 2016
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Researchers in the biomedical engineering department at Case Western Reserve University have found that epileptic activity can spread through a part of the brain in a new way, suggesting a possible novel target for seizure-blocking ...
Jan 24, 2014
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Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain, according to findings ...
Jan 30, 2023
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Scientists at Oregon Health & Science University have identified a long-sought gene-encoded protein that enables the brain to communicate a broad range of signals across gaps between neurons, known as synapses. The discovery ...
Oct 20, 2022
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In neurons, changes in the size of dendritic spines—small cellular protrusions involved in synaptic transmission—are thought to be a key mechanism underlying learning and memory. However, the specific way in which these ...
May 18, 2021
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Researchers from Children's Hospital of Philadelphia (CHOP) have found that dysfunction in an important cell subtype in the brain's neuronal network contribute to chronic symptoms in the neurodevelopmental disorder Dravet ...
Mar 29, 2022
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