A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility. Integrating experiments in fruit flies, mice and human brains, a multi-institutional ...
Aug 13, 2019
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While the harmful effects of amyloid peptide aggregates observed in Alzheimer's disease are well established, the mechanism through which they act on brain cells remains ill-defined. Researchers from CNRS and universite de ...
Jun 12, 2018
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Forty years since its discovery, much remains to be discovered about an enzyme called CaMKII that plays a key role in shaping learning and memory in the brain.
Feb 21, 2020
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In research published in this week's online edition of Science, postdoc Nicholas Vyleta and Professor Peter Jonas of the Institute of Science and Technology Austria uncover the existence of loose coupling between calcium ...
Feb 6, 2014
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UNC School of Medicine researchers have found for the first time a biochemical mechanism that could be a cause of "chemo brain" - the neurological side effects such as memory loss, confusion, difficulty thinking, and trouble ...
Dec 3, 2014
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In people with amyotrophic lateral sclerosis (ALS), changes in neurons appear to activate immune cells. Lowering the inflammation could reduce the symptoms of the disease, according to a study led by Chantelle Sephton, a ...
Jan 10, 2024
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JoAnn Buchanan, Ph.D., was deep into the data. One click at a time, she scanned through the branching, twisting 3D shapes of mouse brain cells on her computer screen. Then Buchanan, a scientist at the Allen Institute, saw ...
Nov 28, 2022
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Amidst the astounding complexity of the billions of nerve cells and trillions of synaptic connections in the brain, how do nerve cells decide how far to grow or how many connections to build? How do they coordinate these ...
Jul 10, 2014
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Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis. The loss of function of an important gene, C9orf72, may affect communication ...
Jun 30, 2021
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A typical characteristic of the brain of an Alzheimer sufferer is the presence of insoluble Tau protein aggregates. Scientists at VIB, KU Leuven and Janssen Pharmaceutica have demonstrated that the distribution of these aggregates ...
May 26, 2015
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