JoAnn Buchanan, Ph.D., was deep into the data. One click at a time, she scanned through the branching, twisting 3D shapes of mouse brain cells on her computer screen. Then Buchanan, a scientist at the Allen Institute, saw ...
Nov 28, 2022
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In a recent search for gene variants associated with Alzheimer's disease (AD), several affected families showed a mutation in an enzyme called protein kinase C-alpha (PKCĪ±). Family members with this mutation had AD; those ...
Nov 28, 2022
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Exposure therapy is one of the leading treatments for post-traumatic stress disorder (PTSD), but up to a half of all patients don't respond to it.
Nov 28, 2022
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A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, researchers at the Jan and Dan ...
Nov 3, 2022
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Tohoku University researchers have shown that Bergmann glial cells, astrocyte-like cells in the cerebellum, "eat" their neighboring neuronal elements within healthy living brain tissue.
Nov 2, 2022
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Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity. Known as inhibitory synapses, these neural connections are rebalanced so that we can consolidate new information ...
Nov 1, 2022
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The correct development of the brain cortex is an essential process for the acquisition of correct cognitive skills. Reelin, a key extracellular protein in neuronal migration and synaptic plasticity, is determinant in this ...
Sep 14, 2022
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A research team from the University of Cologne and the Universities of Mannheim and Heidelberg has found that even the single administration of alcohol permanently alters the morphology of neurons. In particular, the structure ...
Aug 26, 2022
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During development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibitory neuron subtypes are known to influence circuit dynamics, but how they interact with plasticity ...
Aug 24, 2022
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Scientists at the Institute for Auditory Neuroscience, UMG, the Max Planck Institute for Multidisciplinary Sciences and the Abberior Instruments GmbH have applied high-resolution 3D-MINFLUX technology for precise 3D representation ...
Jul 18, 2022
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