Alzheimer's disease & dementia

Untangling the role of tau in Alzheimer's disease

Alzheimer's disease is a brain disorder that causes neurons to die, slowly destroying memory and thinking skills. It's the most common type of dementia, impacting an estimated 50 million people worldwide, and is a particularly ...

Neuroscience

How does the brain learn?

Everyone knows the human brain is extremely complex—but how does it learn, exactly? Well, the answer may be a lot simpler than commonly believed.

Neuroscience

How sleep builds relational memory

Relational memory is the ability to remember arbitrary or indirect associations between objects, people or events, such as names with faces, where you left your car keys and whether you turned off the stove after cooking ...

Diseases, Conditions, Syndromes

Researchers redefine the mechanisms of Dravet syndrome

Researchers from Children's Hospital of Philadelphia (CHOP) have found that dysfunction in an important cell subtype in the brain's neuronal network contribute to chronic symptoms in the neurodevelopmental disorder Dravet ...

Neuroscience

How the brain knows when to take out the trash

The brain has its own housekeeping service, a sophisticated mechanism that cleans up debris that is left over from cellular activity. But scientists have had a hard time figuring out exactly how the brain knows when to initiate ...

Neuroscience

New findings for the function of tau in neurodegenerative disease

Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the "tau interactome" uncovering new findings about the role of tau in neurodegenerative disease. Publishing in Cell, scientists ...

Psychology & Psychiatry

Star cells in the brain render memory flexible

As we live in a dynamically changing environment, it is important for our brain to not only learn new things but also to modify existing memories. This is commonly referred to as "cognitive flexibility." Without this ability, ...

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