Cancer mutation likely trigger of scleroderma
Johns Hopkins scientists have found evidence that cancer triggers the autoimmune disease scleroderma, which causes thickening and hardening of the skin and widespread organ damage.
Dec 5, 2013
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Johns Hopkins scientists have found evidence that cancer triggers the autoimmune disease scleroderma, which causes thickening and hardening of the skin and widespread organ damage.
Dec 5, 2013
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Using mice, lab-grown cells and clues from a related disorder, Johns Hopkins researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in the way certain ...
Oct 9, 2013
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Researchers at the University of Pittsburgh School of Medicine have identified an agent that in lab tests protected the skin and lungs from fibrosis, a process that can ultimately end in organ failure and even death because ...
May 30, 2012
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Thin lips are not only a common cosmetic concern in patients with scleroderma, a condition that involves tightening and hardening of the skin among other effects on internal organs, but also can impact a person's ability ...
Jul 18, 2024
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A cross-disciplinary University of Alberta research team has uncovered a biological marker for scleroderma that can predict which patients will develop severe disease and could also lead to new treatments.
Jan 9, 2024
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Researchers have uncovered cancer-like genetic mutations in the affected cells of people with scleroderma, pointing the way to potential new ways to treat the debilitating and sometimes fatal skin and connective tissue disease.
Oct 20, 2022
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Epigenetic drugs that have shown promise in cancer trials significantly reduce scarring in the cells of patients with scleroderma, an incurable and life-threatening autoimmune disease, a new study shows.
May 9, 2022
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African Americans have more severe complications from systemic sclerosis, also known as scleroderma, than Caucasians. Findings published today in, Arthritis & Rheumatism, a journal of the American College of Rheumatology ...
May 10, 2012
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A genetic pathway previously known for its role in embryonic development and cancer has been identified as a target for systemic sclerosis, or scleroderma, therapy. The finding, discovered by a cross-disciplinary team led ...
Mar 19, 2012
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Systemic scleroderma has slowed Tracy Zinn but it has not stopped her from working. Thanks in part to determination and an accommodating employer, Zinn is now in her 13th year as an account executive for a firm that produces ...
Jul 12, 2011
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