Oncology & Cancer
Breakthrough CAR-T cancer treatments are boosting patients' quality of life
A therapy that bolsters the immune system may not only help certain cancer patients live longer, but better, a new study finds.
Apr 5, 2023
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Page 8 - News tagged with t cell receptor
Oncology & Cancer
Atezolizumab as a primer for chemoradiation is promising for women with locally advanced cervical cancer
Locally advanced cervical cancer remains an area of high therapeutic need, with recent trials failing to demonstrate evidence of benefit from adjuvant chemotherapy or immune checkpoint blockade administered concurrent with ...
Mar 27, 2023
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Oncology & Cancer
Researchers identify key source of T cell 'exhaustion'
Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...
Mar 20, 2023
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Immunology
CAR T cell robots based on magnetic-acoustic actuation developed for precise antitumor immunotherapy
Although chimeric antigen receptor (CAR) T cell therapy has shown potential in the treatment of hematological malignancies, its application in solid tumors is unsatisfactory due to the harsh physical barriers and immunosuppressive ...
Mar 15, 2023
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Oncology & Cancer
Normalizing tumor blood vessels may improve immunotherapy against brain cancer
A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma—the deadliest type of ...
Mar 13, 2023
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Oncology & Cancer
New targets for CAR-T cell therapy against acute myeloid leukemia through AI-assisted analysis
Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically ...
Mar 13, 2023
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Oncology & Cancer
Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy
Scientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found that the gut microbiome may modulate the efficacy of CAR-T cellular immunotherapy CAR-T cells in ...
Mar 13, 2023
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Oncology & Cancer
New CAR T-cell immunotherapy shows promising results for treating blood cancer patients
Blood cancer patients, especially when they relapse, have a poor prognosis, and generally do not survive very long. The last five years have seen success in treating these patients with Chimeric Antigen Receptor (CAR) T-cells—a ...
Feb 24, 2023
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Immunology
Testing their strength: CAR T-cells combat muscle inflammation
Universitätsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the ...
Feb 20, 2023
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Diseases, Conditions, Syndromes
New study identifies T cells involved in the autoimmune disease AAV
Many patients with the autoimmune disease ANCA-associated vasculitis (AAV) suffer a high risk of disease relapse despite treatment. Karolinska Institutet researchers have now identified T cells that contribute to the destruction ...
Feb 16, 2023
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