Chronic bowel inflammation is based on an excessive or misdirected inflammatory reaction. Experts assume that the immune system also reacts incorrectly to microorganisms in the intestine that do not cause an inflammatory ...
Sep 26, 2023
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Chimeric antigen receptor (CAR) T cells have transformed the treatment of refractory blood cancers. These genetically engineered immune cells seek out and destroy cancer cells with precision. Now, scientists at Memorial Sloan ...
Jun 17, 2020
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Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors. Now researchers from the Perelman School of Medicine at the University of Pennsylvania ...
Mar 23, 2020
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CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize ...
Nov 14, 2023
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Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly. One immunotherapy that revitalizes ...
Apr 18, 2022
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When the body is fighting an invading pathogen, white blood cells—including T cells—must respond. Now, Salk Institute researchers have imaged how vital receptors on the surface of T cells bundle together when activated.
Jun 15, 2016
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New research has identified a novel immunotherapy for acute myeloid leukemia. The study, published in Nature Cancer, describes a T-cell receptor that recognizes a mutation shared between a subgroup of patients with the disease. ...
Oct 2, 2023
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Researchers have gained a greater understanding of the biology of staphylococcus skin infections in mice and how the mouse immune system mobilizes to fight them. A study appears this week in the PNAS. Community acquired methicillin-resistant ...
May 15, 2019
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CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ...
Feb 6, 2023
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Primary sclerosing cholangitis (PSC) is a disease in which inflammation causes scars in the bile duct, leading to liver failure, infections, and tumors. Up to 80% of PSC patients have inflammatory bowel disease. Major aspects ...
Mar 17, 2022
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