Medical research

Predicting treatment outcome for leishmaniasis

For patients with cutaneous leishmaniasis, a skin infection transmitted by a sand fly that can in some cases lead to painful and disfiguring ulcers, treatment can be grueling. The first-line therapy offered to many requires ...

HIV & AIDS

Creating viral targets can weaken HIV vaccination

Vaccination against HIV can backfire if the vaccine induces the wrong kind of immune response. Scientists at Emory University's Yerkes National Primate Research Center have evidence—gleaned from several nonhuman primate ...

Medical research

How gene-edited white blood cells are helping fight cancer

For the first time in the United States, a gene editing tool has been used to treat advanced cancer in three patients and showed promising early results in a pilot phase 1 clinical trial. So far the treatment appears safe, ...

Immunology

How do MAIT cells identify and attack foreign invaders?

Melbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their numbers and attack foreign invaders at the site of the infection.

Oncology & Cancer

Researchers find simpler, more effective cancer vaccine approach

Using a precursor to dendritic cells appears to be an efficient and effective way to stimulate the immune system to fight cancer tumors, according to a study in animal and cell models by researchers at the Duke Cancer Institute.

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T cell

T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors (TCR). The abbreviation T, in T cell, stands for thymus, since this is the principal organ responsible for the T cell's maturation. Several different subsets of T cells have been discovered, each with a distinct function.

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