Oncology & Cancer

Drug reprograms immune responses to target glioblastoma

Investigators from Northwestern University Feinberg School of Medicine and The University of Texas MD Anderson Cancer Center have discovered that using a novel drug to target the STING pathway in glioblastoma reprogrammed ...


Boosting CAR-T cell therapies from under the skin

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway. However, ...

Oncology & Cancer

Safer virus helps eliminate cancer in mouse study

Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice. In addition, mice that were treated with this virus were more resistant to developing tumors later in ...

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T cell

T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors (TCR). The abbreviation T, in T cell, stands for thymus, since this is the principal organ responsible for the T cell's maturation. Several different subsets of T cells have been discovered, each with a distinct function.

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