Diseases, Conditions, Syndromes

T-cells with a license to kill viruses

A research group led by Kyoto University has produced the world's first pluripotent stem cell-derived killer T-cell drug to treat COVID-19. The University has filed a patent application ahead of full-scale drug development.

Immunology

T cells and aging: Unraveling the complexities of lifespan

Aging significantly impacts the immune system, notably through the involution of the thymus, which reduces T cell production. This decline weakens immune responses, making older adults more susceptible to infections and diseases. ...

Oncology & Cancer

Blood test may guide use of multiple myeloma immunotherapy

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according ...

Oncology & Cancer

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...

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