Among available immunotherapies, the use of CAR T cells is proving extremely effective against certain blood cancers, but only in half of patients. A main reason for this is the premature dysfunction of these immune cells, ...
Sep 20, 2023
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Research led by the University of Sydney, Australia, has uncovered an important driver of critical SARS-CoV-2 infections. In their paper, "A unique cytotoxic CD4+ T cell-signature defines critical COVID-19," published in ...
Taking a significant leap in the field of vaccine development, University of Western Ontario researchers have discovered a potential "super molecule" that can bolster the effectiveness of several vaccines against viral diseases, ...
Jul 19, 2023
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A Ludwig Cancer Research study has shown that some molecules previously used to treat hypertension might also help the immune system to better target cancer cells. Reported in the current issue of Nature, these findings could, ...
Jun 7, 2023
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Since it was identified in 1984 as the cause of Acquired Immune Deficiency Syndrome (AIDS), the human immunodeficiency virus (HIV) has infected more than 80 million people and been responsible for some 40 million deaths worldwide, ...
May 30, 2023
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A tough battle requires endurance. This is also true for white blood cells as they tackle cancer—or more specifically for T lymphocytes or T cells, a group of white blood cells involved in the immune system's fight against ...
Feb 2, 2023
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An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19. The creators of this therapy, which can successfully ...
Oct 27, 2022
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Immune cells known as lymphocytes have been genetically sequenced in more detail than ever before to investigate how mutations in these cells influence the aging process.
Aug 11, 2022
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Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why. When immune cells called T lymphocytes infiltrate malignant ...
May 9, 2022
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In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity. In a new study, ...
Apr 14, 2022
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