Researchers led by Yasuhiro Murakawa at the RIKEN Center for Integrative Medical Sciences (IMS) and Kyoto University in Japan and IFOM ETS in Italy have discovered several rare types of helper T cells that are associated ...
Jul 4, 2024
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Scientists at St. Jude Children's Research Hospital developed a strategy to improve the ability of engager (ENG) T cells to kill acute myeloid leukemia (AML). The approach showed promise in preclinical models against hard-to-treat ...
Jul 29, 2022
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Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus ...
Feb 2, 2024
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In a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published in Nature, researchers at the Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, introduce a genetic ...
Research led by the Department of Pathology at Stanford University, California, has found that chimeric antigen receptor T (CAR T) cell therapy can potentially result in a reactivation of human herpesvirus 6 (HHV-6) by CAR ...
Immunotherapy is increasingly becoming a successful way to treat cancer. Researchers at Uppsala University have now developed armed CAR-T cells that reinforce the immune defense against cancer and that could increase the ...
Apr 5, 2022
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Endothelial cells—the cells that line blood vessels—grown alongside leukemia cells become corrupted and rescue the cancer cells from many chemotherapy drugs, a study by Weill Cornell Medicine investigators found.
Oct 19, 2022
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A team led by engineers at the University of California San Diego has developed a biodegradable polymer system to treat rheumatoid arthritis, an autoimmune and inflammatory disease, by working in concert with the power of ...
Apr 4, 2023
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Advances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers. Six such CAR-T cell therapies are approved by the Food and Drug ...
Jun 13, 2022
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Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows. The research is still at an early stage, but the drugs used in the study already exist, ...
Feb 25, 2022
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