Checkpoint immunotherapy utilizing PD-1 blockade has become the standard of care for metastatic melanoma. While this treatment is effective in 40% of patients, the other 60% develop resistance, leading to tumor regrowth. ...
Jun 10, 2024
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Cytotoxic T cells are an important component of the immune system. Once activated, they differentiate into either short-lived effector cells or long-lived memory cells. Studies by researchers at ETH Zurich have found that ...
Jun 6, 2024
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The role that Epstein-Barr virus (EBV) plays in the development of multiple sclerosis (MS) may be caused by a higher level of cross-reactivity, where the body's immune system binds to the wrong target, than previously thought.
Jun 6, 2024
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Johns Hopkins Medicine scientists say they have developed an artificial lymph node with the potential to treat cancer, according to a new study in mice and human cells. The newly developed lymph node—a sac filled with immune ...
Jun 6, 2024
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A novel immunotherapy approach developed by Ludwig Cancer Research scientists employs a two-pronged attack against solid tumors to boost the immune system's ability to target and eliminate cancer cells.
Jun 3, 2024
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Researchers have revealed a new method to significantly enhance the efficacy of bispecific antibody therapies in treating solid tumors. Their findings were published on May 13 in Cell Reports Medicine.
May 31, 2024
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A Stanford Medicine study of thousands of breast cancers has found that the gene sequences we inherit at conception are powerful predictors of the breast cancer type we might develop decades later and how deadly it might ...
May 30, 2024
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Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors. One reason for the ...
May 30, 2024
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The research group of Professor Riitta Lahesmaa have discovered a novel modulator for human regulatory T cells. This novel regulator can strengthen or dampen immune response and provides a new basis for therapeutic approaches ...
May 30, 2024
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A new proof-of-concept study by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) shows that changing only a single letter in the DNA code of selected genes in T cells may lead to improved cell therapy. ...
May 29, 2024
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