Probiotic bacteria may enhance anti-cancer activities of the breast cancer drug tamoxifen and other endocrine-targeted therapies, which could help reduce the risk of estrogen receptive positive (ER+) breast cancer, suggests ...
Jun 11, 2022
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A recently discovered enzyme drives the production of a potent form of estrogen in human breast cancer tissue, researchers from the University of Illinois at Chicago College of Medicine have found.
May 18, 2011
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The toxicities associated with aromatase inhibitors (AIs) may explain the lack of overall survival improvement compared with tamoxifen, according to a study published August 22 in the Journal of The National Cancer Institute.
Aug 22, 2011
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(Medical Xpress) -- UCD researchers have identified a novel biomarker that can identify those women with breast cancer who will have a poor response to tamoxifen, one of the principle anti-hormone drugs used to treat the ...
Dec 15, 2011
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(Medical Xpress)—Scientists at The University of Nottingham have identified a protein which could help predict survival outcomes for women with the most aggressive forms of breast cancer.
Sep 7, 2012
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A key protein potentially involved in regulating breast cancer progression has been identified by researchers at Clarkson University in Potsdam, N.Y. Led by professor Costel Darie, the team worked to identify the binding ...
Jan 13, 2012
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Breast cancer is the second most common cancer among women, with more than 200,000 women diagnosed each year. Being exposed to estrogen over a long period of time is one factor that can increase a woman's risk of developing ...
Apr 6, 2011
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While the drug tamoxifen reduces the risk of developing breast cancer and prevents recurrence, the side-effects cause many women to discontinue their treatment. A study involving researchers at Karolinska Institutet in Stockholm ...
Mar 18, 2021
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An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals. The study provides a new path forward ...
Sep 8, 2016
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The well-known drug tamoxifen could exploit a weakness in the physical 'scaffolds' around tumours, according to research led by Imperial.
Dec 11, 2018
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