Neuroscience

Super ager brains contain 'super neurons'

Neurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 years and older) compared to cognitively average peers, individuals with early-stage Alzheimer's ...

Alzheimer's disease & dementia

Untangling the role of tau in Alzheimer's disease

Alzheimer's disease is a brain disorder that causes neurons to die, slowly destroying memory and thinking skills. It's the most common type of dementia, impacting an estimated 50 million people worldwide, and is a particularly ...

Alzheimer's disease & dementia

Key signaling pathway in immune cells could be new Alzheimer's target

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill ...

Alzheimer's disease & dementia

Brain tissue inflammation is key to Alzheimer's disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School ...

Alzheimer's disease & dementia

Good news, bad news from Alzheimer's vaccine trial

An experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to save brain function.

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