Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades. While quality of life and survival are improved with targeted therapies, relapse ...
Jul 13, 2023
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The specific or acquired immune system of vertebrates is a powerful weapon against pathogens and pathologically altered body cells. Here, T cells play a special role. After activation, they can systematically kill off target ...
Jul 13, 2023
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Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, suggest that selectively ...
Jul 6, 2023
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Engineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. However, it hasn't worked as well for solid tumors.
Jul 5, 2023
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Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive ...
Jun 26, 2023
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Tiny packets of molecular cargo shed by cancer cells seed the foundations for metastasis at distant sites in the body.
Jun 19, 2023
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Researchers from The University of Texas MD Anderson Cancer Center found the KRAS G12C inhibitor adagrasib showed promising activity suppressing cancer growth not only within the lungs but also in brain metastases for patients ...
Jun 16, 2023
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Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13 in the open access journal PLOS Biology by ...
Jun 13, 2023
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Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. Now, FMI researchers have identified a DNA region containing multiple regulatory elements that interact ...
Jun 6, 2023
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The RPE and choroid, located behind the human retina, are fundamental to vision, playing a myriad of roles from light absorption to providing oxygenated blood to the photoreceptor cells. However, our understanding of the ...
Jun 1, 2023
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