Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes.
Dec 16, 2020
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For COVID-19 patients with serious lung disease, targeting endothelial cells—cells that comprise the blood vessel wall which regulate oxygen exchange between airways and the bloodstream—may be a novel approach restoring ...
Dec 14, 2020
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Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer. Lead author Amanda Truong, trainee in the McMahon ...
Dec 3, 2020
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For scientists hoping to harness a powerful new technique for demolishing cellular enzymes known as kinases, the choices can be a bit overwhelming. Some 514 different protein kinases toil in human cells, representing 2.5% ...
Dec 3, 2020
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Researchers at the Hong Kong University of Science and Technology (HKUST) have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology. This novel ...
Nov 5, 2020
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T-cells taken from the blood of people who recovered from a COVID-19 infection can be successfully multiplied in the lab and maintain the ability to effectively target proteins that are key to the virus's function, according ...
Oct 26, 2020
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A novel agent that targets a mutated form of the KRAS gene—the most commonly altered oncogene in human cancers and one long considered "undruggable"—shrank tumors in most patients in a clinical trial with manageable side ...
Oct 25, 2020
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Researchers at the Institut de Recerca Sant Joan de Déu (IRSJD) in collaboration with those at Center for Genomic Regulation (CRG) have discovered that RING1B is a critical gene for the development of Ewing sarcoma, a rare ...
Oct 23, 2020
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The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible ...
Oct 9, 2020
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Targeting a "cell survival" protein could be a valuable new approach to treating certain blood cancers associated with Epstein-Barr virus (EBV), according to research resulting from a collaboration between scientists at the ...
Oct 7, 2020
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