Oncology & Cancer

New cancer drug targets accelerate path to precision medicine

In one of the largest studies of its kind, researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival. The team, ...

Oncology & Cancer

Scientists compare methods of drug delivery to malignant tumors

A team of biologists from Sechenov First Moscow State Medical University and Lobachevsky University (Nizhny Novgorod) has analyzed available methods of targeted drug delivery to malignant tumors. Individual approaches to ...

Oncology & Cancer

Starving leukemia cells by targeting amino acids

Cancer cells consume sugar at a higher rate than healthy cells, but they're also hungry for amino acids, the building blocks of proteins and other biomolecules. Researchers at Winship Cancer Institute of Emory University ...

Immunology

Venoms are sources in the search for new medicines

Animal venoms are the subject of study at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets ...

Obstetrics & gynaecology

Folliculin mutations disrupt embryo implantation

New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit ...

Oncology & Cancer

Targeted treatment shrinks deadly pediatric brain tumors

Chemotherapy and radiation are effective cancer treatments because they kill rapidly dividing cells, including tumor cells. But for children—whose tiny bodies are still growing—these treatments can cause lifelong damage. ...

Oncology & Cancer

Regulation and potential drug targets of tumor-associated Tregs

According to estimates from the World Health Organization (WHO), there will be 18.1 million new cases and 9.6 million cancer deaths worldwide in 2018. Cancer is a serious disease that affects people all over the world. And ...

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